Last edited by Tojora
Saturday, May 9, 2020 | History

1 edition of Cocaine hydrochloride found in the catalog.

Cocaine hydrochloride

as the name of the salt formed by cocaine with hydrochloric acid : and a discussion on the nomenclature of alkaloidal salts in general

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  • 14 Currently reading

Published by Druggists" Circular Press in New York .
Written in English


Edition Notes

Reprints from the Weekly Drug News, embracing letters from many eminent chemists.

The Physical Object
Pagination97 pages ;
Number of Pages97
ID Numbers
Open LibraryOL26294433M

Cocaine hydrochloride nasal solution is used to numb the mucous membrane inside the nose before a medical procedure or surgery. This medicine is a local anesthetic. This medicine is to be given only by or under the direct supervision of your doctor. Emergency room visits due to cocaine incidents such as overdoses, unexpected reactions, suicide attempts, chronic effects, and detoxification increased fourfold between and Arrival in the United States. Cocaine hydrochloride—powdered cocaine—was a major cash crop for South American countries, especially Colombia.

Cocaine hydrochloride is the street product that is a white, crystalline powder with a bitter taste and numbing effect.. Cocaine loses its potency in other forms and it is also less soluble. Cocaine must be water soluble so that it can be injected, otherwise the drug can be in clumps when injected which can lead to cardiac arrest. Cite this entry as: () Cocaine Hydrochloride. In: Stolerman I.P. (eds) Encyclopedia of Psychopharmacology. Springer, Berlin, Heidelberg.

Cocaine hydrochloride solution mg/mL 5% in methanol analytical standard for drug analysis Catalog Number C Lot Number SLBRV Storage Temperature 2–8 C CAS RN Synonyms: 3-(Benzoyloxy)azabicyclo-[]octanecaboxylic acid methyl ester hydrochloride, l-Cocaine hydrochloride, Ecgonine methyl ester benzoate. Cocaine is a powerfully addictive stimulant that directly affects the brain. Cocaine has been labeled the drug of the s and ‘90s, because of its extensive popularity and use during this period. However, cocaine is not a new drug. In fact, it is one of the oldest known drugs. The pure chemical, cocaine hydrochloride, has been an abused.


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Cocaine hydrochloride Download PDF EPUB FB2

Cocaine Hydrochloride is the hydrochloride salt form of the tropane alkaloid cocaine, with central nervous systems (CNS) stimulating and local anesthetic activity.

Cocaine binds to the dopamine, serotonin, and norepinephrine transport proteins and inhibits the re-uptake of dopamine, serotonin, and norepinephrine into pre-synaptic neurons.

This leads to an accumulation of the respective. Cocaine hydrochloride is an anesthetic (local) used by health-care professionals prior to surgical procedures that involve the nasal, laryngeal, or oral cavities.

Side effects, drug Cocaine hydrochloride book, warnings and precautions, dosing, storage, pregancy, and breastfeeding.

Solutions of cocaine hydrochloride are incompatible with alkali and with alkaloidal precipitants. {09} Note: Controlled substance in the U.S. COCAINE HYDROCHLORIDE VISCOUS TOPICAL SOLUTION Usual adult dose Anesthetic-vasoconstrictor (mucosal-local) Topical, to the mucosa, as a 1 to 4% solution.

OVERDOSE. The fatal dose of cocaine (cocaine hydrochloride topical solution) has been approximated at g., although severe toxic effects have been reported from doses as low as 20 mg.

Symptoms - The symptoms of cocaine (cocaine hydrochloride topical solution) poisoning are referable to the CNS, namely the patient becomes excited, restless, garrulous, anxious and confused. Cocaine hydrochloride topical solution can be administered by means of cotton applicators or packs, instilled into a cavity, or as a spray.

HOW SUPPLIED. 4% Cocaine Hydrochloride Topical Solution, clear, blue-green solution. NDC Unit-of-Use Glass Bottle filled to contain 4 mL, one 4 mL bottle per carton. Cocaine hydrochloride is a prescription medication used as a local (topical) anesthetic to numb the mucous membranes of the oral (mouth), laryngeal (voice box), and nasal (nose) cavities.

Cocaine hydrochloride belongs to a group of medications called local anesthetics. These work by blocking the pain signals to the brain. Cocaine base is extracted from the paste in informal laboratories. Further processing produces cocaine hydrochloride, a white powder, which is exported.

Once in the United States, the cocaine is cut (diluted) with ingredients such as lactose, and sold or further processed into crack. 3 Citations for Cocaine hydrochloride. Citations are publications that use Tocris products. Selected citations for Cocaine hydrochloride include: Rennekamp et al () σ1 receptor ligands control a switch between passive and active threat responses.

Nat Chem Biol 12 PMID: /5(1). cocaine hydrochloride: a water-soluble salt used for local anesthesia of the eye or mucous membranes. Cocaine hydrochloride is a local anesthetic which blocks initiation or conduction of nerve impulses following local application; when applied topically to mucous membranes, the drug also produces intense vasoconstriction.

When applied topically to the mucous membranes of the nose or mouth, cocaine reduces the acuity of smell or taste, respectively. Cocaine Hydrochloride is a local anaesthetic. Cocaine Solution is used to numb an area of the ear, nose or throat ready for surgery.

It may also be used to reduce bleeding in the area during surgery. Before Cocaine Solution is given Possible side effects include: • restlessness, excitement, a. 4 Recommended Methods for the Identification and Analysis of Cocaine in Seized Materials Adulteration is comparatively rare (but not unknown) for material being internation-ally trafficked with a purity often of % (as cocaine hydrochloride).

Subsequent adulteration and transformation for trafficking purposes usually involves the addition. The heyday of cocaine in our nation’s history was arguably the late s through the early s. In the summer of Richard Pryor set himself on fire while freebasing cocaine, an incident which Pryor mined for a memorable bit in the movie Richard Pryor: Live on the Sunset Strip.

The movie Modern Problems featured a fantasy sequence in which the protagonist, played by Chevy. This book covers everything: the history, Freud, the druglords, the Sandinistas, how cocaine benefits the economies of Peru, Colombia, Bolivia and Mexico, etc.

The author also includes nuggets not found in other books on cocaine, like firsthand accounts of cocaine use dating back hundreds of years, how crack got started, and what "free basing /5(39). Cocaine hydrochloride, which is the powdered form of cocaine, is produced by converting coca paste obtained from the leaves, into the water-soluble salt form that is either snorted or injected into a vein.

Cocaine base, or “crack” cocaine, is the base form of salt, which is usually made using sodium bicarbonate and can be smoked. Blood pressure and heart rate increases were greater with cocaine hydrochloride solution 8% than with COCAINE HYDROCHLORIDE nasal solution.

In the case of an overdose, consult with a certified poison control center () for up-to-date guidance and advice for.

Compound Cocaine hydrochloride with free spectra: 2 NMR, 1 FTIR, and 1 Raman. Cocaine can cause psychological dependence (a strong desire to continue using the medicine because of the "high" feeling it produces). This may lead to cocaine abuse (more frequent use and/or use of larger amounts of cocaine) and to an increased chance of serious side effects.

Cocaine abuse has caused death from heart or breathing failure. A Tale Of Two Addicts: Freud, Halsted And Cocaine In his book An Anatomy of Addiction: Sigmund Freud, William Halsted, and the Miracle Drug Cocaine, medical historian Howard Markel tells the story.

Cocaine Base to Hydrochloride Method Swim was wondering if the following method cobbled together from Argox, Terbium etc posts sounds workable/efficient.

1) Dissolve 1kg Cocaine Base in 12L ether and filter out impurities. 2) Mix ml 31% anhydrous HCl in 1L acetone and add to ether/base mixture and stir well.

3) Boil off ether. Cocaine: A brief history of blow. 15 / Back image author of the new book An and Squibb started making cocaine-containing products - like this vial of cocaine hydrochloride circa Tetracaine is the T in TAC, a mixture of 5 to 12% tetracaine, % adrenaline, and 4 or 10% cocaine hydrochloride used in ear, nose, and throat surgery and in the emergency department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive a: C₁₅H₂₄N₂O₂.Cocaine hydrochloride solution mg/mL±5% in methanol analytical standard for drug analysis Catalog Number C Lot Number SLBDV Storage Temperature 2–8 °C CAS RN Synonyms: 3-(Benzoyloxy)azabicyclo-[]octanecaboxylic acid methyl ester hydrochloride, l-Cocaine hydrochloride, Ecgonine methyl ester benzoate.